{"product_id":"vitamin-d3-k2-4000-iu-100-mcg-120-capsules-by-pure-encapsulations","title":"Vitamin D3 \u0026 K2, 4000 IU\/100 mcg, 120 Capsules, by Pure Encapsulations","description":"\u003cul\u003e\n\u003cli\u003ePromote healthy calcium utilization to maintain bone health*\u003c\/li\u003e\n\u003cli\u003eSupports vascular tissue to support healthy arterial calcium balance and vascular elasticity*\u003c\/li\u003e\n\u003cli\u003eSupports immune function with vitamin D3*\u003c\/li\u003e\n\u003cli\u003eProvides vitamin D3 and vitamin K2 in one convenient capsule\u003c\/li\u003e\n\u003cli\u003e100 mcg of biologically active all-trans vitamin K2 (MK-7) per capsule\u003c\/li\u003e\n\u003cli\u003eMade with hypoallergenic ingredients\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cbr\u003e\u003cstrong\u003eIndications\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eAges 18 and up\u003c\/li\u003e\n\u003cli\u003eBone and vascular health support*\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eSuggested Use\u003c\/strong\u003e\u003cbr\u003eAs a dietary supplement, take 1 capsule daily, with a meal or as directed by a health professional.\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eVerifiable Science\u003c\/strong\u003e\u003cbr\u003eVitamin K2 (menaquinone-7) is a fat-soluble nutrient with an important role in maintaining arterial calcium balance and vascular elasticity.1-12 In a systematic review involving five studies, higher intakes of vitamin K2 were associated with cardiovascular health.10 In an observational study involving 564 postmenopausal women, higher intake of vitamin K2 was associated with calcium balance in the vascular tissue.8 One of the primary functions of vitamin K2 is to support the carboxylation of matrix Gla-protein (MGP), a key protein involved in calcium balance.11 Accordingly, several studies indicate that Vitamin K2 also supports proper utilization of calcium in bone. Clinical research indicates that obtaining adequate amounts helps to maintain bone health.1-6 Vitamin K2 and vitamin D3 both participate in the regulation of osteocalcin, a biomarker of bone formation.1,13*\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSource\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eVitamin K2 (MK-7) is derived from flower extracts geraniol and farnesol\u003c\/li\u003e\n\u003cli\u003eVitamin D3 is derived from lanolin\u003c\/li\u003e\n\u003cli\u003eHypoallergenic plant fiber is derived from pine cellulose\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eWarning\u003c\/strong\u003e\u003cbr\u003eVitamin K may be contraindicated with Coumadin (Warfarin). If you are pregnant or lactating, have any health condition or are taking any medication, particularly blood-thinning medication, consult your health professional before use. It is recommended that individuals taking more than 50 mcg (2,000 IU) vitamin D per day have their blood levels monitored.\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eStorage\u003c\/strong\u003e\u003cbr\u003eStore in a cool, dry place.\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences\u003c\/strong\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eGropper SAS, Smith JL, Groff JL. Advanced Nutrition and Human Metabolism. 5th Ed. Chapter 10, pp. 412-414. Wadsworth\/Cengage Learning, Australia. c.2009.\u003c\/li\u003e\n\u003cli\u003eEl Borolossy R, El-Farsy MS. Eur J Clin Nutr. 2022 Jun;76(6):848-854.\u003c\/li\u003e\n\u003cli\u003eQiu C, Zheng H, Tao H, et al. Mol Cell Biochem. 2017 Sep;433(1-2):149-159.\u003c\/li\u003e\n\u003cli\u003eYamaguchi M, Sugimoto E, Hachiya S. Mol Cell Biochem. 2001 Jul;223(1-2):131-7.\u003c\/li\u003e\n\u003cli\u003eZhang Y, Liu Z, Duan L, et al. Calcif Tissue Int. 2020 May;106(5):476-485.\u003c\/li\u003e\n\u003cli\u003eKnapen MH, Drummen NE, Smit E, et al. Osteoporos Int. 2013 Sep;24(9):2499-507.\u003c\/li\u003e\n\u003cli\u003eKnapen MH, Braam LA, Drummen NE, et al. Thromb Haemost. 2015 May;113(5):1135-44.\u003c\/li\u003e\n\u003cli\u003eBeulens JW, Bots ML, Atsma F, et al. Atherosclerosis. 2009 Apr;203(2):489-93.\u003c\/li\u003e\n\u003cli\u003eMansour AG, Hariri E, Daaboul Y, et al. J Am Soc Hypertens. 2017 Sep;11(9):589-597.\u003c\/li\u003e\n\u003cli\u003eRees K, Guraewal S, Wong YL, et al. Maturitas. 2010 Oct;67(2):121-8.\u003c\/li\u003e\n\u003cli\u003eDalmeijer GW, van der Schouw YT, Magdeleyns E. Atherosclerosis. 2012 Dec;225(2):397-402.\u003c\/li\u003e\n\u003cli\u003eVermeer C and Vik H. Vascul Dis Ther. 2020;5: doi: 10.15761\/VDT.1000179.\u003c\/li\u003e\n\u003cli\u003eGigante A, Brugè F, Cecconi S, et al. J Tissue Eng Regen Med. 2015 Jun;9(6):691-701.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ctable width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003e *These statements have not been evaluated by the Food \u0026amp; Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":43559810826394,"sku":"PE02522","price":35.5,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0525\/8536\/5658\/files\/pure-encapsulations-bone-health-default-title-vitamin-d3-k2-4000-iu-100-mcg-120-capsules-by-pure-encapsulations-29466911473818.jpg?v=1778789334","url":"https:\/\/betterhealthinternational.com\/products\/vitamin-d3-k2-4000-iu-100-mcg-120-capsules-by-pure-encapsulations","provider":"Better Health International","version":"1.0","type":"link"}